Product
| Product name |
NANO ZERO REAL |
| Internal volume |
90 capsules (for 30 days) |
| Name |
Lactic acid bacteria (sterilized) powder contains processed food |
| Manufacturer's suggested retail price |
29,700 JPY（include tax） |
| Raw material name |
Lactic acid bacteria powder (sterilized lactic acid bacteria, dextrin), domestically produced β-nicotinamide mononucleotide, indigestible dextrin, black ginger extract powder, (black ginger extract, dextrin), crystalline cellulose cyclodextrin, HPC/calcium stearate, fine granule dioxide Silicon/shellac carnow halo |
| Nutritional information (3 tablets 900mg) |
| Energy |
3.38kcal |
| Protein |
0.21g |
| Lipid |
0.04g |
| Carbohydrates |
0.55g |
| Equivalent amount of salt |
0.004g |
Thoughts behind the development of NANO ZERO REAL.
Supplements (nutritional supplements) are foods that replenish nutrients that tend to be lacking in daily life.
β-NMN, which is expected to be a rejuvenating ingredient and was approved for production as a food product from a pharmaceutical product in 2020, is a component of the vitamin group originally produced by lactic acid bacteria in the human small intestine.
The same β-NMN produced in the human body is 100% pure β-NMN with few impurities produced by yeast fermentation, but it is very expensive.
By supplementing β-NMN, which is produced in the body as we age, we can maintain youth and health, but the recommended amount of β-NMN required for adults per day is 150 mg to 300 mg.
The Rejuvenation System's main focus is not only on the safety of its ingredients, but also on ``replenishing the power that can no longer be produced.'' In other words, the goal is to train the ability to create β-NMN in your own intestines, absorb it, and convert it into NAD+, which activates sirtuin, which is the key to rejuvenation.
Thoughts behind the development of NANO ZERO REAL.
Supplements (nutritional supplements) are foods that replenish nutrients that tend to be lacking in daily life.
β-NMN, which is expected to be a rejuvenating ingredient and was approved for production as a food product from a pharmaceutical product in 2020, is a component of the vitamin group originally produced by lactic acid bacteria in the human small intestine.
The same β-NMN produced in the human body is 100% pure β-NMN with few impurities, which is produced by yeast fermentation, but it is very expensive.
By supplementing β-NMN, which is produced in the body as we age, we can maintain youth and health, but the recommended amount of β-NMN required for adults per day is 150 mg to 300 mg.
The Rejuvenation System's main focus is not only on the safety of its ingredients, but also on ``replenishing the power that can no longer be produced.'' In other words, the goal is to train the ability to create β-NMN in your intestines like when you were young, absorb it, and convert it into NAD+ by yourself, which activates sirtuin, which is the key to rejuvenation.
The process by which NMN acts on rejuvenation
Step 1
The role of nano-type lactic acid bacteria in regulating the intestinal environment
Nano-type lactic acid bacteria are lactic acid bacteria whose particles have a diameter of less than 1 μm (micron) through nano-processing.
Since it is nano-sized, it is easily absorbed through the Peyer's patches in the small intestine, and has an effect on intestinal immunity and regular intestinal regulation, and has been approved by the Consumer Affairs Agency as a food ingredient with functional claims (improving bowel movement). .
It is important to create an intestinal environment where β-NMN is produced.
Originally, β-NMN is produced by intestinal bacteria together with B1, B2, B3, B5, B6, B7, B9, B12, K2 and folic acid.
It is estimated that the amount of vitamins produced by intestinal bacteria in the intestines of adults accounts for 14-38% of the required amount, a proportion that cannot be ignored.
If you think about it naturally, no matter how much NMN you ingest, it is because other vitamins such as B1, B2, B3, B5, B6, B7, B9, B12, folic acid, and K2 are produced in a well-balanced manner. Regeneration continues.
Because it is produced in your own intestines, the vitamins are well-balanced, absorption is smooth, and subsequent metabolism works smoothly.
Cells work together to release various transmitters and carry out metabolism.
| kinds |
function |
Thiamine
(vitamin B1) |
Helps break down carbohydrates
Stabilizes the mind and supports growth |
Riboflavin
(vitamin B2) |
Helps with cell regeneration and energy metabolism
Creates healthy skin, hair, and nails |
Niacin
(vitamin B3) |
Important for carbohydrate, lipid, and protein metabolism |
| Pantothenic acid (vitamin B5) |
Helps metabolism of lipids, carbohydrates, and proteins
Works on immunity along with vitamin B6 and folic acid |
Pyridoxine
(vitamin B6) |
Creates healthy skin
Involved in the synthesis of neurotransmitters |
Cobalamin
(vitamin B12) |
Helps synthesize and repair nucleic acids and proteins in nerve cells
Prevents pernicious anemia |
Biotin
(vitamin B7) |
Helps hair and skin health
Also associated with fatigue and depression |
Folic acid
(vitamin B9) |
Important for anemia prevention
Helps protein and nucleic acid synthesis |
Menaquinone
(Vitamin K2) |
Related to blood coagulation
Also important for bone metabolism |
Step 2
Polymethoxyflavone derived from black ginger
This ingredient has been approved by the Consumer Affairs Agency as a food ingredient with functional claims.
- Reduces abdominal fat for those with a high BMI.
- Makes it easier to consume fat during energy metabolism during daily activities.
- Maintaining the walking ability of middle-aged and elderly people.
It is important to be able to convert absorbed β-NMN into NAD+ (nicotinamide adenine dinucleotide).
It is said that after the age of 50, NAD+ decreases to half of its peak level when young, accelerating aging.
As the amount of NAD+ increases, sirtuin genes become activated. The strengthened sirtuin genes actively protect mitochondria and telomeres, increasing skeletal muscle mass.
Absorbed β-NMN is converted to NAD+, which decreases with aging.
When NAD+ is synthesized in the hypothalamus of the brain, the sirtuin gene SIRT1 is activated, leading to improvements in physical activity ability and sleep quality. Also, when NAD+ is synthesized in the hippocampus of the brain, it leads to improved memory and learning ability. When NAD+ is synthesized in the retina, it leads to improved optic nerve cell function. The improvement of these three effects is expected to have a synergistic effect when taken together with our supplement Milagro AG.
Types of NMN
There are two types of NMN: α-NMN and β-NMN. Safe NMN is β-NMN, which is the same that is produced in the human body. The other is α-NMN, and its safety is unknown. There are many cheap NMN mixed with α-NMN on the market.
NANO ZERO REAL uses 100% β-NMN.
Manufacturing method of NMN
1. Synthesis method: using catalyst
Contains ingredients that are not permitted to be used in Japan under the Food Sanitation Act. Synthetic methods generally tend to leave behind impurities, and many products use ingredients that are not permitted under Japan's Food Sanitation Law. (Used in cosmetics, etc.)
2. Enzyme method: using enzymes
Materials from China undergo final processing using enzyme methods (using chemicals) at a Japanese factory, making them domestically produced. Since it is not a pure fermentation method, impurities tend to remain and there is no guarantee of safety.
3. Fermentation method: Fermentation with yeast
The reason why we insist on using yeast fermentation to produce NMN is because it is extremely similar to β-NMN produced in the intestines. NANO ZERO REAL is made using 100% yeast fermentation method.
Express the safety of ingredients in a way that anyone can understand.
NANO ZERO REAL requests an external organization to inspect the quality of its products so that safety can be confirmed at a glance.
Product quality certificate / ingredient content certificate
NANO ZERO REAL discloses the ingredient certificate and content certificate for each lot.
When choosing NMN supplements, we recommend choosing products that have a certificate of safe β-NMN and a content certificate.
Traceability system
We want to deliver safety and security to everyone involved with NANO ZERO REAL.
With safety and security as our motto, we trace every step of the manufacturing management, storage management, and delivery management process, from manufacturing to the delivery of the product, and record and store all data in an effort to manage the safety and security of our products.
At Rejuvenation Systems, we strictly control the manufacturing, shipping, warehousing, and shipping of NANO ZERO REAL to dealers to ensure product reliability and safety. With the motto of safety and security, we trace every step of the manufacturing management, storage management, and delivery management process, from manufacturing to the delivery of the product, and record and store all data in an effort to manage the safety and security of our products. .
If you take a photo of the QR code on the side of the product using your smartphone's camera mode, the yellow button in the photo (cert.reju.jp) will appear. When you press this yellow button, the certificate will be displayed. You will usually see a blue Certificate of Authenticity. If a red "counterfeit" sign appears on the product, it is not an officially manufactured product and is a fraudulent product. Copy products of Milagro AG have been sold several times in the past. If you see a fake product, please check the store where you purchased it and contact the police.
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